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Project & Chemistry Expertise Summary

Our primary expertise is the research and development of challenging chemistry processes which are 1-20 reaction steps in length. Rather than promote expertise in a specific technology or reaction, our core strength is instead in our ability to skillfully manage each & every piece of the sophisticated chemistry and wide range of conditions required in these types of lengthy routes and new development programs. Our chemists can design the entire route themselves, or simply optimize a literature or customer provided route. Customers often like to start work with us in the very early stages where quantities are small and chemistry undeveloped. Our low production cost base and commercial production capabilities, also make us a supplier of choice for working on a wide range of pilot and commercial production projects as well. In those cases, our clients utilize our ability to design and develop greener, lower-cost processes for their anticipated regular commercial production. This work is performed at both our USA and China sites, and proposals quoted in price per gram kilo, or on FTE basis.

Process Design & Custom Synthesis

The SYNBEST owned & core partner sites combine to include over 100 experienced R&D personnel with expertise in custom chemical synthesis. We have years of experience designing creative, multi-step routes to produce high yields of complicated and challenging molecules in a wide range of volumes from milligrams to metric tons. Flexibility in any situation is one of our most well-known assets, and we can comfortably develop chemistry that can meet an urgent requirement, or change focus and investigate hundreds of reaction parameters to fine-tune process efficiency for the future. We are also experienced in the art of impurity profiling, and all the analytical method development and process design required to meet any challenging impurity specification. Our partners gain exceptional value by combining our top-of-the-line process design expertise with our unparalleled pilot- and large-scale production capabilities.

Pilot and Commercial Production

With multiple specialized facilities and over 700 personnel with expertise in production, site management, environmental health and safety, and quality assurance, SYNBEST is an able partner at any step of the production process. We have the equipment and expertise to work at the gram scale for optimization, the kilogram scale for pilot production, and the metric ton scale for full commercial production. Our core network of sites gives us the luxury of having a wide range of specialized production equipment, which allows us to successfully handle a wider range of chemistry processing conditions, and ultimately improves the project cost and lead time for our clients. Our experienced scientists fluently implement both chemical processes we design or optimize ourselves, and pathways that we recieve directly from the customer.